The Phrase Mental Health on a Sheet of Fabric

Why Highly Sensitive People Face Higher Risks of Depression and Anxiety: Insights from a New Meta-Analysis

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written by abdullah sagheer

August 23, 2025

Do you ever feel extremely moved by strong lights, slight variations in mood or even by the company of crowds? You could be in a category that has been termed as highly sensitive. This is not an issue of emotions alone because it is a scientifically identified character trait called environmental sensitivity.

A new systematic review and meta-analysis in Clinical Psychological Science (2025) identifies that environmental sensitivity is tightly tied to mental health outcomes and more specifically depression and anxiety.
This study is based on 33 studies and the participation of more than 12,000 people that prove high sensitivity may increase the vulnerability to psychological distress in people.

Defining Environmental Sensitivity.

Environmental sensitivity (also referred to as sensory-processing sensitivity) is the degree to which people respond to both outer and inner stimulation.

Sensitive individuals are very sensitive, they may pay attention more to the little things, get overwhelmed with loudness or emotions, and they may process more deeply.

Approximately, 31 percent of individuals are severely sensitive, 40 percent are moderate and 29 percent are lowly sensitive

In a contrast with widespread personality characteristics including, but not limited to, neuroticism or introversion, the sensitivity is not a generic characteristic, but is rather biological in nature. According to brain imaging and fraternal/identical twin studies, there is a genetic component and some degree of associated activity in portions of the brain involved in empathy and reflection

It does not mean sensitivity is a fault, it is a part of human diversity in the way the world is processed. It however comes with its own challenges.

A surreal portrait of a young adult with closed eyes, glowing neural pathways, and light particles across the face. One half of the background shows busy city crowds and bright lights, while the other half shows calm nature with trees and flowing water symbolizing the contrast between overstimulation and serenity in highly sensitive people

The link to Mental Health

The new review compared studies that gauged the level of sensitivity using instruments such as the Highly Sensitive Person Scale (HSPS) and the clinical analysis scores of depression and anxiety.

The important findings have been the following:

Association with depression strong

In the case of the meta-analysis, there was a moderate effect size (r =.36), which validates that high sensitivity is a significant risk factor of experiencing depressive symptoms

Strong correlation to anxiety

Sensitivity also demonstrated strong correlation with anxiety (r =.39), and thus very sensitive people tend to have social phobia, generalized anxiety, or panic-related disorders

Other mental problems

Sensitivity showed relationships with obsessive compulsive, PTSD, agoraphobia and psychosomatic symptoms, but fewer studies of each.

Why Does Sensitivity Lead to Vulnerability?

Researchers theorize that the difficulties experienced by sensitive people with mental health could be because of a few mechanisms:

Overstimulated: Sensitive people are sensitive to a lot more things which causes frequent feelings of overwhelm, and a sense of helplessness.

Weight of processing: This can cause the person to ruminate, which exposes him or her to depressive tendencies.

Higher emotional reactivity: Emotional reactivity is so high that a negative mood is likely to last longer and coping skills will further exacerbate this disposition

In small words, sensitivity intensifies positive and negative events. Without support, the disadvantages can outvibe the advantage.

The Silver Lining: Being Sensitive Is a strength

It is not all bad news in the story. Sensitivity also causes people to be more receptive to positive places and interventions.

Therapy outcomes: HSPs respond better to psychotherapy, and academic prevention programs, as well as mindfulness practices

Good things:They tend to feel better when positive things happen, more creative, and more valuing of art and relationships.

This implies that sensitivity is a two-edged sword; a threat in the harsh environment but a useful resource in the good environment.

Mental-health Implications

The results of this meta-analysis present useful conclusions to the collective and guiding principles to the medical community:

Early identification

Sensitivity screening among adolescents can be used to determine those that are more likely to develop depression and anxiety.

Tailored therapy

The clinicians would be able to adjust the therapy depending on the sensitivity level in such a way that the less sensitive clients would be treated in a more caring and supportive manner.

Lifestyle support

Stress reduction, mindfulness, and balance in routines are worth trying to cope with overstimulation of sensitive people.

Reducing stigma

Instead of seeing sensitivity as an irregular personality, it should be viewed as a normal personality aspect that should not be viewed as a problem. This also promotes more people to seek help.

Conclusion

It suggests that being (emotionally) sensitive to the world does have an emotional price to pay: the costs are just as significant as all agreements. With the help of appropriate support, however, these qualities may result in resilience, creativity and improved relationships.

The authors indicate that environmental sensitivity should not be overlooked with regard to mentality health research, prevention as well as treatment. Now is the time we should take an entirely different view of sensitivity so as to regard it as strength of uniquely human nature which, supplemented, can serve to healthier lives.


Reference

Falkenstein, T., Sartori, L., Malanchini, M., Hadfield, K., & Pluess, M. (2025). The relationship between environmental sensitivity and common mental-health problems in adolescents and adults: A systematic review and meta-analysis. Clinical Psychological Science. https://doi.org/10.1177/21677026251348428

Disclaimer: The information provided on this blog is for educational and informational purposes only and is not intended as medical advice. While we strive to share accurate and up-to-date research, this content should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or a qualified healthcare provider with any questions regarding a medical condition. We do not make any warranties about the completeness, reliability, or accuracy of this information. Any action you take based on the content of this blog is strictly at your own risk. This blog summarizes and interprets publicly available scientific research. We are not affiliated with the original authors or institutions.

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